Anti-aging & texture · Acne & breakouts · Texture & pores · Topical
Adapalene / Niac
Adapalene / Niacinamide 0.1/4% Cream · 0.1/4%
A third-generation retinoid (adapalene) paired with niacinamide, listed for texture and acne.
Starting at $44.50/mo. Billed every 2 months. Cancel anytime. Skip or delay refills. Your plan covers whichever formula a provider prescribes.
- Actives
- Adapalene, Niacinamide
- Formulary strength
- 0.1/4%
- Form
- Cream
- Size
- 30g / 60g
- Routine
- Topical
- Status
- Prescription only
- Price
- $44.50/mo, billed $89 every 2 months. Cancel anytime. Skip or delay refills (care plan, not a per-formula quote)
What would you like to discuss?
Choosing a concern does not choose or guarantee this prescription.

What is in it
The actives, explained.
Adapalene
A third-generation retinoid applied to the skin.
Niacinamide
A form of vitamin B3 used on the skin to support the skin barrier.
Ingredient education only. It does not say this formula is right for you or what it will do.
How it is used
Dr. Malouf’s protocol.
The usual starting directions from Dr. Malouf. Your provider sets your final directions, and the pharmacy label is what you follow.
- Directions
- Pea-size to the whole face at night, every other night for 2 weeks, then nightly.
- Breaks and limits
- Gentler option for sensitive skin.
- Every day
- SPF 30+ every morning. Moisturizer as needed.
- Amount
- Pea-size covers the whole face; for spot formulas, use a thin layer on the spots only.
Cautions to discuss with your provider
- Stop and message the care team if: pregnant, trying or breastfeeding; blistering, swelling, crusting or burning that lasts; rash; skin darkening or a blue-gray color (hydroquinone).
- Can cause dryness and irritation, especially early on. Increases sun sensitivity. Tell your provider about pregnancy, plans or breastfeeding.
- Generally well tolerated; occasionally causes flushing or irritation.
- Prescription only. A licensed provider decides whether it is appropriate; approval is not guaranteed.
General safety information, not a complete list. Your intake asks about medicines, allergies, pregnancy and health history.
Questions
About this formula.
Is this prescribed to me if I choose it?
No. You cannot choose a prescription from this page. A licensed provider reviews your medical intake and decides whether this formula, a different one or none is appropriate.
How would I use it?
Pea-size to the whole face at night, every other night for 2 weeks, then nightly. SPF 30+ every morning. Moisturizer as needed.
The usual starting directions from Dr. Malouf. Your provider sets your final directions, and the pharmacy label is what you follow.
What should I know about compounding?
CutisRx prescriptions may be custom compounded by a licensed pharmacy. Compounded medications have not been approved by the FDA, and the FDA does not review them for safety, effectiveness or quality before they are dispensed. Ingredient information on this site is education only. Your prescriber decides whether a compounded medication is appropriate for you.
What will it look like when it arrives?
A standard pharmacy bottle, jar or pump with a pharmacy label showing your name, the formula, its strength and your provider’s directions. The photograph on this page is a lifestyle image, not the actual packaging.
What about pregnancy or breastfeeding?
This formula contains at least one ingredient that is not used, or needs particular care, in pregnancy or breastfeeding. Tell your provider if you are pregnant, planning a pregnancy or breastfeeding.
What does it cost?
Your plan price covers whichever formula a provider prescribes: $44.50/mo, billed $89 every 2 months. Cancel anytime. Skip or delay refills. The amount due today, including the one-time $20 review fee per new treatment, is shown at checkout. Your card is authorized at checkout and charged only if the provider approves.
Start with the concern, not the formula.
Choose your concern
$44.50/mo, billed $89 every 2 months. Cancel anytime. Skip or delay refills. A licensed provider in our network decides whether treatment is appropriate.